Introduction
Esophageal cancer remains one of the most lethal malignancies, with survival rates plummeting to approximately 10% when diagnosed at advanced stages. However, early detection can significantly improve prognosis, with survival rates reaching up to 90%. Recently, a novel imaging technique has been developed to identify precancerous and cancerous changes in esophageal tissue at earlier stages.
Innovative Imaging System
Researchers at Helmholtz Munich in Germany have introduced O2E, a capsule-based endoscopy system that integrates optical coherence tomography and optoacoustic imaging. While optical coherence tomography provides detailed visualization of tissue microstructures, optoacoustic imaging employs light pulses to detect ultrasound signals from blood vessels deep within tissues. Combined, these modalities produce high-resolution three-dimensional images of the esophagus’s structure and function, with sensors capable of capturing comprehensive 360-degree views.
Preliminary Studies
In preliminary studies involving animal models and human tissue samples with Barrett’s esophagus—a known precursor to esophageal cancer—the team succe...