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Screening for Parkinson's disease across questionnaires using language models

Diego Fabrício
Published on 2026-11-04 00:00:00
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Screening for Parkinson's disease across questionnaires using language models

Health questionnaires have the potential to facilitate early disease detection. However, differences in question wording and formats often prevent artificial intelligence (AI) models trained on one questionnaire from performing well on another. Quest2Dx encodes the meaning of each question–response pair, which enables it to screen for Parkinson’s disease on questionnaires it never encountered during training.

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References

Dorsey, E. R. et al. Global, regional, and national burden of Parkinson’s disease, 1990–2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet Neurol. 17, 939–953 (2018). A systematic analysis that establishes Parkinson’s disease as the fastest-growing neurological disorder, with pr...

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