Peptides can assemble into two-dimensional ultrathin materials with programmable structures and functions, but maintaining crystallinity and stability is challenging. Now, a metal-directed assembly strategy enables mechanical weaving of peptides to provide highly durable and modular two-dimensional peptide crystals with molecular-level precision.
This is a preview of subscription content, access via your institution
Access options
Access Nature and 54 other Nature Portfolio journals
Get Nature+, our best-value online-access subscription
$32.99 / 30 days
cancel any time
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Rent or buy this article
Prices vary by article type
from$1.95
to$39.95
Prices may be subject to local taxes which are calculated during checkout
References
Li, Z., Cai, B., Yang, W. & Chen, C.-L. Chem. Rev. 121, 14031–14087 (2021).
Nam, K. T. et al. Nat. Mater. 9, 454–460 (2010).
Yuan, C. et al. Nat. Rev. Chem. 3, 567–588 (2019).
Kaygisiz, K., Sementa, D., Athiyarath, V., Chen, X. & Ulijn, R. V. Nat. Rev. Mater. 10, 449–472 (2025).
Bruns, C. J. & Stoddart, J. F. The Nature of the Mechanical Bond: From Molecules...

