Week 2 of the 2026 NFL season features several division matchups and a handful of teams looking to avoid an 0-2 start.
The Vikings and Bears meet in Chicago after both won their openers. Minnesota's aggressive defense, led by coordinator Brian Flores, will test quarterback Caleb Williams and an offense that scored 59 points in Week 1. The Bengals visit Houston with Joe Burrow dealing with back tightness and the Texans potentially without receiver Nico Collins.
The Browns visit Tampa Bay with Baker Mayfield playing against a Cleveland that took him No. 1 overall before giving up on him. Cleveland's defense allowed 34 points in Week 1 and generated just four pressures. The Buccaneers also lost their opener.
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Jacksonville visits Denver in a matchup of quarterbacks Trevor Lawrence and Bo Nix. The Jaguars have scored at least 23 points in 12 consecutive games, while Denver features one of the NFL's better defenses.
Other notable matchups include the Saints at Ravens, Steelers at Patriots, Packers at Jets, Eagles at Titans, Raiders at Chargers and Seahawks at Cardinals. The Giants visit the Rams on Monday night.
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